Investigate the metabolites found in Drosophila .
Metabolite Explorer
The log2 fold-change (FC) in metabolite intesity levels between Drosophila aged and 7 day old flies.
The metabolites in this list have a high confidence score having been identified by a standard compound libary or by fragmentation analysis. Expansion of these trems can be found in the Glossary
| Metabolite | 0 Days (F) | 0 Days (M) | 10 Days (F) | 10 Days (M) | 20 Days (F) | 20 Days (M) | 30 Days (F) | 30 Days (M) | 40 Days (F) | 40 Days (M) | 50 Days (F) | 50 Days (M) | 60 Days (F) | 60 Days (M) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L-proline | -0.73 | -0.61 | -0.86 | -0.93 | -1.51 | -1.53 | -1.15 | -0.99 | 0.17 | -0.12 | -1.36 | -0.87 | 0.46 | 0.42 |
| proline | -0.52 | -3.46 | -0.68 | -3.15 | -1.97 | -5.09 | -1.39 | -4.44 | 0.76 | -3.60 | -1.44 | -4.50 | 1.58 | -2.25 |
| glycine betaine | -3.41 | -2.90 | -1.73 | -1.54 | -0.58 | -1.56 | -1.13 | -1.07 | 0.27 | -0.05 | -1.80 | -1.58 | 1.69 | 1.13 |
| L-valine | -0.01 | 1.23 | -1.36 | -1.42 | -0.51 | -1.57 | -0.90 | -1.33 | 1.49 | 0.00 | -2.07 | 0.10 | 1.81 | 0.12 |
| guanine | -1.94 | -0.91 | -0.50 | -0.43 | -0.50 | -0.80 | -0.43 | -0.28 | 0.33 | 0.14 | -1.01 | -0.68 | 1.75 | 1.37 |
| Xanthine | -0.32 | -0.14 | -0.04 | -0.09 | 0.01 | -0.69 | -1.09 | -1.52 | 2.46 | 1.89 | 0.13 | -0.55 | 1.96 | 0.78 |
| hypoxanthine | -0.90 | -0.54 | 0.04 | 0.10 | -0.17 | -0.98 | -0.46 | -1.30 | 2.66 | 2.44 | 0.46 | -0.01 | 2.93 | 1.99 |
| phosphocholine | -0.30 | 0.00 | -0.09 | -0.31 | -0.12 | -0.66 | 0.45 | 0.07 | 0.73 | -0.01 | -0.41 | 0.29 | 0.99 | 0.96 |
| 4-(trimethylammonio)butanoate | -2.73 | -1.79 | -0.59 | 0.00 | -0.64 | 0.24 | -0.50 | 1.55 | 1.41 | 1.24 | 0.70 | 0.98 | 4.19 | 4.01 |
| N(pros)-methyl-L-histidine | 0.47 | 0.27 | -1.03 | -0.65 | -2.41 | -2.05 | -1.64 | -1.95 | -0.99 | -1.41 | -0.97 | -1.52 | -1.07 | -0.73 |
| N-acetyl-L-glutamic acid | -0.48 | -0.25 | -0.04 | -0.39 | -0.37 | -0.78 | 0.11 | -0.01 | 0.54 | -0.02 | -0.17 | -0.21 | 1.58 | 1.14 |
| (R)-2-hydroxyglutaric acid | -0.13 | 0.53 | 0.81 | 1.00 | 0.06 | 0.11 | -0.05 | -0.21 | 1.70 | 1.36 | 0.58 | 0.52 | 2.95 | 2.14 |
| N-acetylhistamine | -4.54 | -5.08 | -0.86 | -0.75 | -2.78 | -1.08 | -2.60 | -1.12 | -0.63 | -0.20 | 1.91 | -6.61 | -0.45 | 1.04 |
| nicotinic acid | -1.21 | -1.49 | 0.56 | 0.29 | -0.25 | -0.04 | -1.54 | -1.03 | 3.52 | 4.19 | -0.12 | -0.21 | 3.57 | 3.42 |
| 2'-deoxyadenosine | -1.50 | -1.46 | -0.93 | -1.56 | -1.01 | -1.15 | -1.30 | -1.28 | 0.89 | 1.29 | -1.34 | -1.46 | 1.10 | 1.12 |
| N(2)-acetyl-L-ornithine | -0.19 | -2.16 | -0.50 | -2.20 | -0.17 | -2.71 | -0.62 | -2.64 | 0.57 | -1.52 | -0.71 | -1.99 | 1.21 | -0.75 |
| urocanic acid | -0.18 | 0.10 | -0.64 | -0.74 | 0.23 | -0.11 | -0.44 | 0.11 | 0.40 | -0.02 | 1.08 | -0.38 | 0.11 | -0.54 |
| (R)-pantothenic acid | -0.52 | 0.07 | -0.92 | -0.88 | -1.61 | -1.36 | -0.10 | -0.32 | 1.08 | 0.91 | -1.01 | 0.14 | 1.43 | 1.30 |
| L-leucine | -0.44 | 0.94 | -1.29 | -1.23 | -0.58 | -1.68 | -0.94 | -1.28 | 1.76 | 0.18 | -2.20 | 0.46 | 1.98 | 0.72 |
| L-kynurenine | -2.33 | -0.63 | 0.25 | -0.30 | -0.79 | -0.44 | -0.32 | -0.23 | 0.51 | 0.04 | -2.60 | 1.50 | 1.08 | 0.59 |
| N(2)-acetyl-L-lysine | -0.09 | 0.52 | -0.33 | -0.45 | - | - | -1.11 | - | 1.25 | 0.48 | - | -1.35 | 0.22 | -0.25 |
| histidine | -0.51 | -1.07 | -2.21 | -0.60 | -0.34 | -0.34 | -0.91 | 0.06 | 0.18 | 0.75 | 0.67 | -1.46 | 0.05 | 1.22 |
| L-histidine | -0.35 | -1.58 | -2.61 | -0.71 | -0.44 | -0.52 | -1.21 | -0.10 | -1.71 | -0.96 | 0.63 | -1.79 | -1.67 | -0.16 |
| pyridoxine | -2.44 | -1.47 | -1.42 | -1.36 | -1.55 | -1.54 | -1.25 | -1.11 | -0.36 | -0.11 | -1.64 | -1.26 | 0.90 | 0.95 |
| 3-hydroxykynurenine | -0.04 | 0.20 | -0.20 | -0.47 | -0.16 | -0.47 | 0.00 | -0.25 | -0.38 | -0.26 | -0.73 | -0.24 | 0.34 | 0.64 |
| L-glutamine | -0.38 | 0.05 | -0.23 | -0.79 | -0.42 | -0.80 | -0.09 | -0.19 | 0.29 | -0.36 | -1.29 | 0.14 | 1.02 | 0.62 |
| Alanyl-Glycine | -3.03 | -2.89 | -1.32 | -1.17 | -0.88 | -1.02 | -0.79 | -0.59 | 0.82 | -0.19 | -1.16 | -0.80 | 1.42 | 0.96 |
| L-serine | 0.67 | 1.19 | 0.45 | 0.21 | 0.70 | 0.88 | 0.74 | 0.30 | 1.30 | 0.42 | 0.40 | 1.83 | 1.63 | 0.83 |
| 5-oxo-L-proline | -2.00 | 0.60 | 0.69 | -1.43 | -0.31 | -0.65 | 1.78 | 0.95 | 2.65 | 1.74 | -1.96 | 0.25 | 3.53 | 2.26 |
| pyruvic acid | -0.79 | -0.54 | -0.25 | -0.53 | -0.22 | -1.33 | -0.29 | -1.22 | 1.14 | 0.85 | 0.27 | 0.64 | 1.95 | 1.46 |
| sucrose | -2.83 | -3.49 | -1.13 | -1.82 | -1.11 | -2.38 | 0.57 | 0.52 | -1.01 | -1.15 | -0.48 | -0.80 | 0.22 | 0.73 |
| maltose | 3.08 | 3.51 | 1.23 | 0.84 | 0.60 | 0.91 | 1.63 | 1.47 | 0.07 | -0.03 | 2.06 | 1.54 | 1.40 | 1.08 |
| L-citrulline | -0.31 | -0.24 | 0.05 | -0.09 | 0.94 | -0.24 | 0.68 | 0.90 | 0.04 | 0.38 | 0.52 | -0.55 | 2.17 | 1.86 |
| (R)-carnitine | -1.34 | -1.15 | -1.56 | -1.65 | -2.25 | -2.27 | -1.56 | -1.31 | -0.95 | -0.69 | -2.01 | -2.37 | -0.51 | 0.53 |
| phthalic acid | -0.19 | -0.18 | -0.86 | -1.31 | -1.28 | -0.92 | -1.15 | -0.51 | -1.26 | -1.41 | 0.23 | -0.32 | -1.22 | -1.25 |
| xanthurenic acid | -2.97 | -2.71 | -0.39 | -0.54 | -0.69 | -0.86 | -0.41 | -0.54 | 0.10 | 0.00 | -0.90 | -0.46 | 0.33 | 0.55 |
| 2-amino-2-deoxy-D-glucopyranose | 1.49 | 0.74 | 0.76 | 0.30 | 0.78 | -0.62 | 0.84 | -0.14 | -0.34 | -1.05 | 0.95 | 0.40 | 0.67 | -0.19 |
| guanosine | -0.78 | -0.67 | 0.14 | -0.25 | 0.37 | -0.16 | 0.33 | 0.39 | 1.18 | 0.36 | -0.40 | 0.26 | 1.80 | 1.05 |
| D-mannitol | -3.28 | -2.58 | -1.44 | -1.30 | -2.47 | -2.79 | -2.95 | -2.40 | -2.12 | -1.34 | -3.96 | -3.27 | -0.53 | 0.11 |
| kynurenic acid | 0.12 | 1.37 | -0.76 | -1.43 | -1.63 | -1.93 | -0.73 | -0.59 | 0.58 | 0.34 | -1.99 | 0.28 | 1.05 | 0.44 |
| L-arginine | -0.41 | -0.14 | -0.73 | -0.87 | -0.87 | -0.82 | -0.61 | -0.42 | 0.16 | -0.18 | -0.61 | -0.44 | 0.62 | 0.48 |
| gamma-aminobutyric acid | -2.20 | -1.45 | -0.89 | -0.77 | -1.05 | -1.19 | -0.93 | -0.76 | 0.23 | 0.01 | -1.25 | -1.12 | 1.48 | 0.57 |
| 3-aminobutanoic acid | -1.78 | -1.67 | -1.69 | -1.52 | -1.53 | -1.61 | -1.56 | -1.74 | -0.88 | -0.75 | -1.67 | -1.71 | -0.78 | -0.69 |
| D-fructofuranose | 0.99 | 2.14 | -1.08 | -0.73 | -1.23 | -1.16 | -0.99 | -0.68 | 0.94 | 0.82 | -1.54 | -0.66 | 2.31 | 1.78 |
| O-acetylcarnitinium | -0.46 | -0.78 | -0.85 | -0.74 | -2.35 | -1.50 | -1.83 | -1.32 | -0.63 | 0.45 | 0.15 | -1.56 | -1.76 | 1.10 |
| 2-phospho-D-glyceric acid | 0.12 | 0.85 | 0.87 | 0.03 | -0.11 | -0.13 | 0.93 | 0.72 | 1.20 | 1.70 | -0.53 | 1.18 | 2.55 | 2.58 |
| L-cystine | -0.18 | 0.78 | 1.04 | 0.92 | 0.93 | 0.51 | 0.42 | 0.37 | 0.62 | -0.02 | 0.60 | 0.88 | 1.39 | 1.59 |
| L-methionine | -0.73 | 0.54 | -1.32 | -1.15 | -1.12 | -1.49 | -1.69 | -1.58 | 1.00 | -0.74 | -1.84 | -0.03 | 1.03 | -0.10 |
| L-tryptophan | 1.30 | 1.21 | -0.41 | 0.14 | -0.25 | -0.55 | 0.05 | -0.07 | 1.65 | 0.78 | 0.39 | -0.49 | 1.88 | 1.18 |
| cytosine | -2.01 | -0.33 | -1.03 | -1.85 | -2.09 | -2.21 | -2.23 | -2.05 | -1.15 | -1.69 | -3.98 | -0.71 | -0.57 | -0.51 |
| Imidazole-4-acetate | -0.78 | -0.13 | -1.22 | -1.52 | -2.56 | -2.04 | -1.70 | -0.88 | -0.12 | -0.40 | -1.12 | -1.64 | 0.02 | 0.41 |
| adenosine | -0.62 | -1.45 | 0.84 | 0.26 | -1.65 | -0.38 | -0.24 | -1.11 | -0.45 | -0.88 | 0.87 | -0.47 | -0.63 | 0.06 |
| spermine | -2.21 | -2.40 | -2.31 | -2.37 | -2.28 | -2.32 | -2.27 | -2.20 | -0.45 | -0.47 | -2.23 | -2.36 | -0.40 | -0.63 |
| L-gulono-1,4-lactone | -1.42 | -1.47 | 1.59 | 1.42 | 2.11 | 1.46 | 2.55 | 2.18 | 0.49 | 0.37 | 1.34 | 0.70 | 1.83 | 1.47 |
| adenine | -3.03 | -1.83 | -0.71 | -0.28 | -1.33 | -0.92 | -2.60 | -2.16 | -2.95 | -1.43 | -0.68 | -1.83 | -0.74 | -0.26 |
| L-phenylalanine | 0.55 | 1.46 | -1.19 | -1.06 | -0.55 | -1.42 | -1.09 | -1.07 | 2.03 | -0.08 | -1.90 | 0.23 | 2.16 | 0.59 |
| L-glutamic acid | -1.62 | -0.57 | -0.42 | -0.90 | -0.54 | -1.07 | -0.63 | -0.99 | 0.57 | 0.04 | -1.15 | 0.02 | 0.78 | 0.70 |
| trans-4-hydroxy-L-proline | 2.74 | 3.06 | -1.00 | -0.73 | -0.39 | -0.54 | -0.64 | -0.08 | 0.12 | -0.37 | -0.56 | -1.09 | 0.76 | 0.28 |
| (R)-lactic acid | 0.65 | 1.25 | 1.07 | 1.31 | -0.22 | 0.10 | -0.04 | 0.73 | 0.67 | 0.69 | 0.83 | 1.13 | 2.77 | 2.52 |
| 3',5'-cyclic AMP | -0.51 | 0.06 | -0.59 | -0.88 | -0.75 | -0.71 | -0.20 | -0.21 | 0.11 | -0.09 | -0.30 | -0.38 | 1.61 | 1.29 |
| Polypropylene glycol (m w 1,200-3,000) | -1.81 | -1.83 | -1.62 | -1.80 | -1.75 | -1.79 | -1.60 | -1.69 | -3.08 | -2.01 | -1.83 | -1.76 | -1.97 | -2.42 |
| D-threose | -3.54 | -2.62 | -1.55 | -1.56 | -1.48 | -1.70 | -1.10 | -0.53 | 0.08 | 0.31 | -1.59 | -1.26 | 1.96 | 2.23 |
| choline alfoscerate | -2.69 | -3.02 | -0.48 | -1.86 | -2.25 | -1.83 | -0.62 | -1.28 | 1.54 | 2.85 | -1.01 | -1.84 | 2.97 | 2.87 |
| L-lysine | 0.80 | 2.23 | 0.32 | -0.05 | 0.01 | 0.01 | -0.01 | 0.50 | 1.50 | 0.02 | -0.98 | 1.38 | 2.12 | 1.15 |
| inosine | -0.65 | -0.10 | 0.31 | 0.13 | -0.13 | -0.63 | -0.21 | -0.32 | 1.47 | 1.11 | -0.39 | 1.00 | 1.99 | 1.68 |
| L-asparagine | 2.09 | 2.63 | 1.34 | -0.06 | 0.77 | 0.03 | 1.31 | 0.16 | 1.39 | -0.11 | 0.60 | 1.87 | 1.78 | 0.22 |
| 3-hydroxyphenylacetic acid | -0.60 | -0.01 | -0.40 | 0.15 | -0.63 | -0.09 | -0.41 | 0.20 | -0.63 | -0.44 | -0.96 | 0.04 | 0.53 | 0.34 |
| taurine | -0.15 | -0.44 | 0.03 | -0.26 | 0.02 | -0.33 | 0.13 | 0.11 | 0.20 | 0.34 | 0.39 | -0.73 | 0.63 | 0.51 |
| D-glucopyranose 6-phosphate | -1.51 | -1.32 | -0.69 | -1.55 | -1.71 | -1.59 | -0.89 | -0.40 | -1.02 | -2.70 | -2.49 | -0.70 | -0.66 | -0.73 |
| allantoin | -0.96 | -0.39 | 0.69 | 0.49 | -0.37 | -0.58 | -0.74 | -0.22 | 1.68 | 1.27 | -0.32 | 0.22 | 0.44 | 0.76 |
| succinic semialdehyde | -1.44 | -1.23 | -1.23 | -1.02 | -1.04 | -1.23 | -0.93 | -1.11 | 0.13 | 0.11 | -0.88 | -1.01 | 0.77 | 0.67 |
| D-gluconic acid | -2.32 | -2.63 | 0.92 | 0.62 | 1.34 | 0.78 | 1.82 | 1.53 | -0.22 | -0.20 | 0.70 | 0.02 | 1.26 | 0.92 |
| glutathione | -0.85 | -0.56 | -0.61 | -0.11 | -1.41 | -1.54 | 0.75 | -0.20 | -0.84 | -1.41 | -0.67 | 0.19 | 0.13 | -0.04 |
| (S)-malic acid | -1.48 | -0.04 | -0.86 | -1.91 | -0.93 | -1.70 | -0.55 | -0.35 | -0.59 | -1.20 | -3.37 | -0.31 | 0.87 | 0.72 |
| L-gamma-glutamyl-L-cysteine | -0.89 | 0.36 | 0.29 | 0.63 | -0.28 | -0.40 | 0.18 | 0.00 | 0.25 | -0.32 | -0.42 | 1.42 | 1.06 | 1.48 |
| Adenosine 2',5'-bisphosphate | 0.26 | 1.11 | 0.79 | 0.05 | -0.38 | -0.23 | 0.34 | 0.36 | -0.15 | -0.77 | -0.56 | 0.62 | 0.50 | 0.70 |
| methyl L-tyrosinate | -0.78 | -0.92 | -1.01 | -1.05 | -0.73 | -1.39 | -0.91 | -1.50 | -0.52 | -0.58 | -1.08 | -1.29 | 0.71 | 0.67 |
| triethanolamine | -3.13 | -2.70 | -3.04 | -2.16 | -2.94 | -2.28 | -0.22 | -0.41 | -0.57 | -0.53 | -1.89 | -1.88 | -1.24 | -0.85 |
| bis(2-ethylhexyl) phthalate | 0.05 | -0.75 | -0.77 | -0.80 | -0.61 | -0.70 | -0.54 | -0.63 | 0.52 | -0.19 | -0.66 | -0.74 | -0.43 | -0.43 |
| 5'-S-methyl-5'-thioadenosine | -0.84 | 0.51 | 0.17 | -1.07 | -1.34 | -0.90 | -0.86 | -0.29 | -1.06 | -0.92 | -0.91 | -0.36 | -0.90 | 0.16 |
| tributyl phosphate | -2.71 | -3.27 | -2.98 | -3.45 | -2.99 | -3.06 | -3.63 | -3.98 | 1.41 | -0.76 | -3.16 | -3.46 | -0.68 | 1.19 |
| glutathione disulfide | -1.73 | -1.34 | -1.24 | -0.99 | -1.33 | -2.11 | 0.63 | 0.05 | -1.30 | -2.05 | -0.86 | 0.04 | -0.36 | -0.72 |
| N,N-diethyl-m-toluamide | -1.16 | -1.26 | -1.11 | -1.49 | -1.06 | -1.18 | -2.14 | -2.00 | -0.41 | -0.42 | -0.61 | -0.91 | - | -1.00 |
| diisopropyl hydrogen phosphate | -3.15 | -3.39 | -3.53 | -3.72 | -3.39 | -3.24 | -4.49 | -3.80 | -0.87 | -1.48 | -3.29 | -3.48 | -0.88 | -0.26 |
| 15(R)-hydroperoxy-EPE | 0.87 | -1.64 | - | - | -2.32 | -0.99 | -0.51 | -1.65 | - | - | 0.22 | -1.66 | - | - |
| choline | -3.40 | -2.55 | -1.12 | -1.16 | -1.36 | -1.76 | -1.23 | -1.42 | 0.97 | 0.43 | -1.76 | -1.09 | 2.12 | 0.86 |
| Octadecadienoate | -0.44 | -0.22 | 0.15 | 0.76 | -0.01 | 0.53 | -0.24 | -0.05 | 1.85 | 2.04 | 0.43 | 0.36 | 3.02 | 2.31 |
| citric acid | -1.68 | -0.25 | -1.24 | -1.55 | -1.13 | -1.19 | -0.55 | -0.15 | -1.73 | -1.98 | -1.93 | -0.42 | -0.11 | 0.78 |
| adenosine 5'-monophosphate | -1.12 | -0.91 | -0.49 | -0.50 | -0.50 | -0.50 | -0.16 | -0.06 | -0.02 | -0.13 | -0.72 | -0.19 | 0.54 | 0.90 |
| guanosine 5'-monophosphate | -0.43 | 0.62 | 1.01 | -0.03 | -0.04 | -0.29 | 0.10 | 0.27 | 0.00 | -0.55 | -1.03 | 0.52 | 0.73 | 0.75 |
| L-cystathionine | -0.18 | -0.36 | -0.33 | -0.57 | 0.38 | -0.85 | 0.39 | -0.21 | 0.13 | -0.61 | -0.40 | 0.06 | 1.74 | 0.54 |
| (2R,3S)-2-methylcitric acid | -4.57 | -3.67 | -0.50 | -0.49 | -0.93 | -0.65 | -0.35 | 0.76 | -0.44 | 0.07 | -0.89 | -0.52 | 2.01 | 2.29 |
| myristoleic acid | -3.26 | -0.66 | 0.02 | -0.45 | 0.25 | -0.59 | 0.04 | -1.39 | 0.07 | 0.35 | -4.10 | 0.65 | 1.75 | 1.15 |
| riboflavin | -0.90 | -0.26 | -0.24 | -0.22 | 0.20 | 0.23 | 0.75 | 0.93 | 0.62 | 1.11 | -0.03 | 0.44 | 2.01 | 2.20 |
| cytidine | -1.39 | -0.14 | 0.34 | -0.58 | -0.56 | -0.79 | -0.71 | -0.65 | 0.67 | -0.19 | -2.53 | 0.78 | 1.02 | 1.18 |
| S-methylcysteine | - | - | 0.64 | -2.63 | -0.60 | - | -1.04 | - | -0.38 | -2.97 | - | -2.29 | 0.79 | - |
| 2'-deoxyadenosine 5'-monophosphate | -2.12 | 0.08 | 0.79 | -1.02 | -0.44 | -0.03 | -0.48 | -0.07 | 0.23 | -0.80 | -3.43 | 1.68 | 0.67 | 1.10 |
| 4-guanidinobutanoic acid | 0.00 | 1.17 | -1.15 | -1.10 | -1.36 | -1.69 | -0.87 | -0.92 | 0.68 | 0.08 | -2.06 | -1.05 | 1.33 | 0.95 |
| orotic acid | -1.20 | 0.49 | -0.32 | -1.27 | -0.99 | -1.03 | -0.47 | -0.72 | 0.35 | -0.46 | -0.32 | -0.41 | 1.08 | 0.19 |
| uridine | -1.84 | -1.14 | -1.84 | -1.99 | -2.27 | -2.69 | -2.18 | -2.33 | 0.22 | -0.48 | -2.97 | -1.38 | 0.80 | 0.67 |
| cytidine 5'-monophosphate | -2.08 | -0.67 | 0.54 | -0.63 | -0.42 | -0.37 | -0.32 | 0.11 | -0.07 | -0.26 | -2.49 | -0.18 | 0.57 | 0.58 |
| uridine 5'-monophosphate | -2.47 | -1.51 | -0.04 | -0.87 | -0.91 | -0.86 | -0.12 | 0.18 | -0.93 | -2.21 | -1.16 | -1.37 | -0.21 | -0.62 |