FlyMet Search Pathways

Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type	Adult F/W p-value	Adult M/W p-value	Larvae/W p-value
Carcass	0.00004259556155971171	0.9953245794517627	0.00000000012791988620833124
MSpermatheca	0.0000000001444978328787714	nm	nm
Midgut	0.0000000000000000000008787480203152046	0.000000000000000000000000000004780341632670492	0.0000000000000000000005977861869109896
Trachea	nm	nm	0.0000000000000012209157435808908
Brain	0.0000000000000000005847439653890035	0.00000000013723279191339609	0.000000000000000024207458749384705
Tubules	0.000000000000000000003602855839241076	0.000000000000000000000000000000000000000000009708284124295333	0.00000000000000006501859831060448
VNC	0.00000000017606254389445977	0.000009097568011016446	nm
Eye	0.000000000000000000000029578039226713394	0.0000000000006522351710308418	nm
Salivary Gland	0.000021099559078134803	0.00000000572570431479189	0.00000000000000000018129991314039949
Ovaries	0.0000000004732673599026678	nm	nm
Muscle	0.0000021658411786367246	0.004430516878569264	nm
VSpermatheca	0.0000017246754535553626	nm	nm
Accessory Gland	nm	0.000000000000039237184915060406	nm
Hindgut	0.0000000003883676143480801	0.0004967711973609169	0.00000000000000021224617233823776
Testes	nm	0.00000000000009986053160376199	nm
Rectal Pad	0.0000010347709875437578	0.000000021143711093658624	nm
Fat Body	0.00000000000001606094631845641	0.00000000000000000035800556349388	0.0000000000000000000022404693507655867
Hemolymph	0.00003171130132650944	0.0001825075664305185	0.00000000000000000001954463944680236
Crop	0.000000000019957019804028996	0.00000039274029368417097	nm
Head	0.00000000000024737310323243524	0.00000000000000000000000000000004285690365804499	nm
Heart	0.0000000000005408118999194347	0.0004980320451503599	nm

In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet