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Changes observed in the Histidine catabolism metabolites and enzymes found in Drosophila tissues
Log2 FC Adult female/Whole Fly:
Tissue-Type L-Histidine Histamine Carnosine Anserine SAM SAH HDC CARNMT1
Whole fly 0.00 0.00 0.00 ND 0.00 ND 0.00 0.00
Head* -4.91 -5.30 -25 ND -6.0 ND 2.87 2.70
Eye - - - - - - - -
Brain / CNS - - - - - - - -
Thoracicoabdominal ganglion - - - - - - - -
Crop - - - - - - - -
Midgut* -8.19 -5.05 -25 ND -9.54 ND -4.64 2.46
Hindgut - - - - - - - -
Malpighian Tubules - - - - - - - -
Fat Body - - - - - - - -
Salivary gland - - - - - - - -
Heart - - - - - - - -
Trachea - - - - - - - -
Ovary* -7.55 -25 -25 ND -7.28 ND -25 4.75
Carcus - - - - - - - -
Rectal pad - - - - - - - -

*Real Data


Log2 FC Adult Male/Whole Fly:
Tissue-Type L-Histidine Histamine Carnosine Anserine SAM SAH HDC CARNMT1
Whole fly 0.00 0.00 0.00 ND 0.00 ND 0.00 0.00
Head* -5.62 -25 -25 ND -6.08 ND 3.01 2.20
Eye - - - - - - - -
Brain / CNS - - - - - - - -
Thoracicoabdominal ganglion - - - - - - - -
Crop - - - - - - - -
Midgut* -7.52 -25 -25 ND -9.54 ND -6.64 2.5
Hindgut - - - - - - -
Malpighian Tubules - - - - - - - -
Fat Body - - - - - - - -
Salivary gland - - - - - - - -
Heart - - - - - - - -
Trachea - - - - - - - -
Virgin Spermatheca - - - - - - - -
Mated Spermatheca - - - - - - - -
Testis* -6.31 -25 -25 ND -9.54 ND -4.32 2.07
Accessory glands - - - - - - - -
Carcus - - - - - - - -
Rectal pad - - - - - - - -

*Real Data


Log2 FC Larvae/Whole Fly:
Tissue-Type L-Histidine Histamine Carnosine Anserine SAM SAH HDC CARNMT1
Head* - - - - - - - -
Eye - - - - - - - -
Brain / CNS - - - - - - - -
Thoracicoabdominal ganglion - - - - - - - -
Crop - - - - - - - -
Midgut* - - - - - - - -
Hindgut - - - - - - - -
Malpighian Tubules - - - - - - - -
Fat Body - - - - - - - -
Salivary gland - - - - - - - -
Heart - - - - - - - -
Trachea - - - - - - - -
Ovary - - - - - - - -
Virgin Spermatheca - - - - - - - -
Mated Spermatheca - - - - - - - -
Testis* -3.36 -25 -25 - -8.84 - - -
Accessory glands - - - - - - - -
Carcus - - - - - - - -
Rectal pad - - - - - - - -

*Real Data


Histidine Catabolism

Pathway Coverage
Assigned Metabolite Formulas Total Pathway Formulas Expressed Genes Total Pathway Genes
4 6 2 2