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Serotonin and melatonin biosynthesis and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type Adult F/W p-value Adult M/W p-value Larvae/W p-value
Carcass 0.000000000000000000009668890853576085 0.000000000000000005671694940644751 0.00000000004843987238529
MSpermatheca 0.0000000000000000000000003718832953005159 nm nm
Midgut 0.00000000000000000000000000004663237649074998 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568550066458262 0.00000000000000000000031038114726465697
Trachea nm nm 0.00000000000000037339875403089236
Brain 0.00000000000000000000000000000000001647072803526007 0.000000000000000027371588269588114 0.0000000000000000030777462878999586
Tubules 0.0 0.0000000000000000001204872472594377 1.0
VNC 0.000000000000000011044810702176228 0.00000000000000003919075274136997 nm
Eye 0.000000000000000464683719136745 0.0000000000000001606900292861314 nm
Salivary Gland 0.00000000000001704152357412681 0.0000000000000014239340277939415 0.00000000000000000006444368900312015
Ovaries 0.0000000000000003059799794809754 nm nm
Muscle 0.000000000000000046665875972284894 0.000000000000000000000000003343619693094119 nm
VSpermatheca 0.0000000000007186141141442235 nm nm
Accessory Gland nm 0.0000000000000000000000000008821453620448793 nm
Hindgut 0.0000000000000000000026914545659796566 0.0 0.000000000000000010087121425744112
Testes nm 0.000000000000000034068382996608086 nm
Rectal Pad 0.000000000000000025176551504981065 0.000000000000001399630369518177 nm
Fat Body 0.000000000000000000005098426451673113 0.000000000000000000000000000000025059279734425934 0.000000000000000000001180335801017832
Hemolymph 0.000000000000000000000000000000000000005982411775352316 0.00000000000000006851639752465587 0.000000000000000000008295087963913256
Crop 0.00000000000001905223765376919 0.00000000000000000000000000000000000000000015439094958393744 nm
Head 0.000000000000000040625697846337934 0.0000000000000000000000000013525005965450967 nm
Heart 0.00000000000000000023348758009938675 0.00000000009068591694737518 nm

In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet

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