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Regulation of pyruvate dehydrogenase (PDH) complex and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type Adult F/W p-value Adult M/W p-value Larvae/W p-value
Carcass 0.00000037634350390143723 0.0000488642385365456 0.0000000001850416912468371
MSpermatheca 0.000000000028305088442048077 nm nm
Midgut 0.000000000000000025008997264676562 0.00000000000000027859089062061565 0.0000000000000000000009656149069923388
Trachea nm nm 0.0000000000000008316718080359898
Brain 0.000000000000008848404877369747 0.0000000032330793848377603 0.00000000000000003303810645831407
Tubules 0.0000000000000000000000000000012391361875895442 2.426281885795583e-176 0.00000000000000005933637359133393
VNC 0.00000000001620779419306741 0.00000008265518617861464 nm
Eye 0.0000000000000019067787201506567 0.00000000013725787822675608 nm
Salivary Gland 0.00000004286583899468205 0.0000002644632005696753 0.0000000000000000002104150406196625
Ovaries 0.0000000001994601828548479 nm nm
Muscle 0.000000014248625682568115 0.0000007935458557892226 nm
VSpermatheca 0.0005028831937587244 nm nm
Accessory Gland nm 0.00000000000000000001135523953393985 nm
Hindgut 0.0000000027086540163917884 0.000000000000015643431550443453 0.00000000000000026617363758008277
Testes nm 0.000000000019643149823005333 nm
Rectal Pad 0.0008276926610993507 0.00000007516191887580015 nm
Fat Body 0.000000000000003566874400838875 0.0000000000000005410329831774368 0.0000000000000000000020070091622694334
Hemolymph 0.2699972279169514 0.024309272814090375 1.0
Crop 0.000005985828187360604 0.000010480505147204265 nm
Head 0.0000000005697093304747205 0.00000000000000000005193023154171018 nm
Heart 0.0000000000060728405654391926 0.0025725371951548955 nm


In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet

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