FlyMet Search Pathways

PAOs oxidise polyamines to amines and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type	Adult F/W p-value	Adult M/W p-value	Larvae/W p-value
Carcass	0.00021892954737344017	0.0006696093026693464	0.23819302618688654
MSpermatheca	0.1686140246863826	nm	nm
Midgut	0.08785314043542669	1.0	0.00000000000000000019560306303192518
Trachea	nm	nm	0.000000000000000000000015522235095719714
Brain	0.9999948489627581	1.0	0.00000000000000008161193861343496
Tubules	0.00003101044052853835	0.00012608934645936472	0.6045726660892471
VNC	0.0736759798508025	1.0	nm
Eye	0.9999980749548157	1.0	nm
Salivary Gland	0.13033041557750014	1.0	0.00000000000000000000000365024771983982
Ovaries	0.059518695124587295	nm	nm
Muscle	0.8928321876221429	1.0	nm
VSpermatheca	0.05180429094988567	nm	nm
Accessory Gland	nm	1.0	nm
Hindgut	0.9377158198988197	0.9657558286671213	0.000000003650559807446109
Testes	nm	0.0000000000000000018259068797291452	nm
Rectal Pad	0.8690013078941973	0.9278929145252495	nm
Fat Body	0.00017486911754946004	0.000179987260446285	0.0000000000000000000000000000004228290359716045
Hemolymph	0.00000001386550569788632	0.00020842712614592301	0.00000000000000000005376320609472768
Crop	0.8637543744460457	0.9002260497116692	nm
Head	0.7339444277079157	1.0	nm
Heart	0.9235618965651338	1.0	nm

In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet