FlyMet Search Pathways

PAOs oxidise polyamines to amines and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type	Adult F/W p-value	Adult M/W p-value	Larvae/W p-value
Trachea	nm	nm	0.000000000000000000000015522235095719714
Muscle	0.8928321876221429	1.0	nm
Ovaries	0.059518695124587295	nm	nm
Testes	nm	0.0000000000000000018259068797291452	nm
Heart	0.9235618965651338	1.0	nm
Hindgut	0.9377158198988197	0.9657558286671213	0.000000003650559807446109
Fat Body	0.00017486911754946004	0.000179987260446285	0.0000000000000000000000000000004228290359716045
Crop	0.8637543744460457	0.9002260497116692	nm
Head	0.7339444277079157	1.0	nm
Salivary Gland	0.13033041557750014	1.0	0.00000000000000000000000365024771983982
Brain	0.9999948489627581	1.0	0.00000000000000008161193861343496
VNC	0.0736759798508025	1.0	nm
Tubules	0.00003101044052853835	0.00012608934645936472	0.6045726660892471
MSpermatheca	0.1686140246863826	nm	nm
Carcass	0.00021892954737344017	0.0006696093026693464	0.23819302618688654
Eye	0.9999980749548157	1.0	nm
VSpermatheca	0.05180429094988567	nm	nm
Midgut	0.08785314043542669	1.0	0.00000000000000000019560306303192518
Hemolymph	0.00000001386550569788632	0.00020842712614592301	0.00000000000000000005376320609472768
Accessory Gland	nm	1.0	nm
Rectal Pad	0.8690013078941973	0.9278929145252495	nm

In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet