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Glucagon-like Peptide-1 (GLP1) regulates insulin secretion and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type Adult F/W p-value Adult M/W p-value Larvae/W p-value
Trachea nm nm 0.00000000000000020557018418668997
Muscle 0.00000000000000000016630339003364854 0.0000000000000000012258895285131614 nm
Ovaries 0.00000000000000000013692372539725422 nm nm
Testes nm 0.000000000000002309465807743372 nm
Heart 0.0000000000000000000000013944623761812727 0.00000000001774937510251379 nm
Hindgut 0.000000000000000000000000483946542676955 0.0 0.00000000000000003762005184053528
Fat Body 0.00000000000000000000033284491609510314 0.00000000000000000000000000000000034430009010751285 0.00000000000000000000038806580274381206
Crop 0.00000000000000034949818862416277 0.000050191158547595064 nm
Head 0.0000000000000000014735017531644895 0.0000000000000004826091168839437 nm
Salivary Gland 0.000000000000000041988818601727944 0.000000000000014136463492308246 0.00000000000000000004773953754016404
Brain 0.0000000000000000000000000000000000000751633062666119 0.0000000000000022033781385544407 0.000000000000000004355632044373148
VNC 0.0000000000000000014124366018482961 0.000000000000000008317398885401331 nm
Tubules 0.000000000000000000000000000000000000000000018353432238824545 0.0 0.00000000000000003601558193572034
MSpermatheca 0.000000000000000000000000000000314382864502183 nm nm
Carcass 0.000000000000000000000008096405562793661 0.00000000000000000041522823112318667 0.00000000007282180519991759
Eye 0.00000000000000000000000000000012779769553710094 0.000000000001512836789060615 nm
VSpermatheca 0.00000000000006073470659337962 nm nm
Midgut 0.000000000000000000000000000000008298961456080376 0.00000000000000000000000000000000000000000000000000004191609752408717 0.00000000000000000000010318025629183653
Hemolymph 0.00000000000000000000000000000000000000000000000000000002691508451011583 0.00003803469108150465 0.000000000000000000003459959225565383
Accessory Gland nm 0.0000000000000000000000000000016227219653068456 nm
Rectal Pad 0.00000000000000000000007145486886798217 0.000000000000000008581005827774939 nm

In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet

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