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Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type Adult M/W p-value Larvae/W p-value Adult F/W p-value
Salivary Gland 0.000000000000756788495155243 0.00000000000000000014232642909433567 0.0000000000000028453437148974733
Tubules 0.00000000009047228849743048 0.4736237802800366 0.0000000000012963151921001492
Brain 0.0000000000020611141306964656 0.000000000000000007245754702002435 0.0000000000000000000005602950022536967
Trachea nm 0.0000000000000007547964564402889 nm
MSpermatheca nm nm 0.0000000000000000000005437481024689602
Testes 0.0000012967207970182618 nm nm
VSpermatheca nm nm 0.000000000002688810389968331
Hindgut 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015988540053037053 0.00000000000000019020849770409662 0.000000000000000000050808967014881015
VNC 0.000000000000005606491574294189 nm 0.00000000000000002519309593829214
Heart 0.000000019635797305455562 nm 0.0000000000000000008408122914641899
Hemolymph 0.00000010774247771878758 0.0000000000000000026954290258220044 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000010226364655639114
Fat Body 0.000000000000000000000027601108975071753 0.0000000000000000000038721371539184345 0.00000000000000000016351928946937704
Accessory Gland 0.000000000000002612617941914715 nm nm
Midgut 0.00000000000000000000000000000000000000000000000000000000000000000049312528039712245 0.00000000000000000000032410612728403077 0.00000000000000000000000000000000021549329603190085
Carcass 0.000009122837133194657 0.00000000009321222296341816 0.0000000000000000005066649136586746
Rectal Pad 0.000000022041572230710436 nm 0.00000000025389935706219166
Muscle 0.000000000000000013958670586072166 nm 0.0000000000000003914501401921292
Eye 0.0001197203916144643 nm 0.0000000001408226641666704
Ovaries nm nm 0.0000000000000000011617857680103357
Crop 0.000000000000000000000000000000000002595072676683299 nm 0.00000000000011358446166883054
Head 0.00000001984481286272004 nm 0.000000027732203285566522


In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet

Selected Pathway