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Abacavir metabolism and metabolites found in Drosophila tissues.

The smallest p-values reveal tissues with the most significant changes in the pathway metabolites, between whole flies and individual tissues.

Tissue-Type Adult M/W p-value Larvae/W p-value Adult F/W p-value
Salivary Gland 0.00000027137429196493075 0.0000000000000000006988048451440445 0.013395803058146631
Tubules 0.000000000007331706863728218 0.0000000000000011799975990884561 0.000000014768864103202428
Brain 0.0068421796460777 0.000000000000000015155868749353797 0.00007867746909556665
Trachea nm 0.000000000000005170756262453388 nm
MSpermatheca nm nm 0.000000001075718293692634
Testes 0.00015326224236149067 nm nm
VSpermatheca nm nm 0.00003388842342000544
Hindgut 0.21212927182560742 1.0 0.006831430988190048
VNC 0.000004220780267804391 nm 0.000013820649664945226
Heart 0.1007570369632651 nm 0.0000030632063559766197
Hemolymph 0.0456860754445658 1.0 0.00013389584069125923
Fat Body 0.0000000024698468400577174 0.000000000000000000007162001006806633 0.00000000004861367632040937
Accessory Gland 0.0062941431425631005 nm nm
Midgut 0.000000007389358642758739 1.0 0.00000003678747981732127
Carcass 0.00006047214540328915 1.0 0.000004687814384481398
Rectal Pad 0.04017990978899069 nm 0.44067668831351126
Muscle 0.001670506792713976 nm 0.00015947474568418608
Eye 0.29014772392365207 nm 0.000012665059119347933
Ovaries nm nm 0.00000001521826689163477
Crop 0.000006361790819653869 nm 0.0000000024095183690027657
Head 0.12371416629735582 nm 0.0010714104564611823


In this diagram the overrepresentation shown as ReactomeH highlights compounds (with associated peaks) that are found in FlyMet

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